Gemcitabine With Ascorbate Including Adolescents
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Bone Sarcoma
- Metastatic Bone Sarcoma
- Metastatic Soft Tissue Sarcoma
- Soft Tissue Sarcoma
- Unresectable Bone Sarcoma
- Unresectable Soft Tissue Sarcoma
- Type
- Interventional
- Phase
- Early Phase 1
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 13 years and 17 years
- Gender
- Both males and females
Description
The primary objective of the expansion cohort of this pilot study is to evaluate preliminary evidence of anti-tumor activity of intravenous ascorbate in combination with gemcitabine as assessed by overall response rate to inform a subsequent Phase II trial.
The primary objective of the expansion cohort of this pilot study is to evaluate preliminary evidence of anti-tumor activity of intravenous ascorbate in combination with gemcitabine as assessed by overall response rate to inform a subsequent Phase II trial.
Tracking Information
- NCT #
- NCT04877587
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: William Terry, MD University of Iowa Hospitals & Clinics
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