Feasibility of a Novel Process-based Treatment for Patients With Psychosis
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Bipolar Disorder, Current Episode Depressed, Severe, With Psychotic Features
- Bipolar Disorder, Current Episode Manic Severe With Psychotic Features
- Brief Psychotic Disorder
- Delusional Disorder
- Unspecified Psychosis Not Due to a Substance or Known Physiological Condition
- Major Depressive Disorder, Recurrent, Severe With Psychotic Symptoms
- Major Depressive Disorder, Single Episode, Severe With Psychotic Features
- Manic Episode, Severe With Psychotic Symptoms
- Other Psychotic Disorder Not Due to A Substance or Known Physiological Condition
- Schizoaffective Disorder
- Shared Psychotic Disorder
- Schizophrenia
- Schizotypal Disorder
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentIntervention Model Description: Incoming patients from the clinic of Max Planck Institute of Psychiatry are continuously screened for study eligibility and - after they have given informed consent - are assigned to the experimental treatment condition.Masking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 70 years
- Gender
- Both males and females
Description
Due to the enormous economic and social costs of psychotic-spectrum disorders, increasing the effectiveness of treatment options has become an important subject for psychiatric research. Latest findings in the field of psychotherapy for psychosis show some promising results for so-called Process-bas...
Due to the enormous economic and social costs of psychotic-spectrum disorders, increasing the effectiveness of treatment options has become an important subject for psychiatric research. Latest findings in the field of psychotherapy for psychosis show some promising results for so-called Process-based Therapies (PBT) such as the Metacognitive Training (MCT) and Acceptance and Commitment Therapy (ACT) (Barnicot et al., 2020). Instead of trying to change the content of psychotic symptoms such as hallucinations and delusions, PBT directly address cognitive processes, which have been found to maintain the disorder's symptomatology (Hayes et al., 2020). While MCT focusses on changing patients' cognitive biases by inducing metacognition (Moritz & Woodward, 2007), ACT works with psychological processes such as mindfulness, willingness and cognitive distancing (Gaudiano & Herbert, 2006). There is a growing study base for PBT in a psychotic outpatient setting, research in non-ambulatory settings though is rare (Barnicot et al., 2020). Therefore, the aim of the current study is to develop and test the feasibility and safety of a new process-based group therapy program for acute psychotic patients. The five-week treatment approach will consist of three different modules combining interventions from both MCT and ACT (Module I: Psychoeducation, Module II: Metacognition, Module III: Cognitive Defusion). First preliminary effectiveness and process measures (PANSS, BPRS, WHO-DAS, CGI, BCIS and CFQ) will also be included in order to inform the design of future research. Thus, the study will give valuables insights in the feasibility and effectiveness of an innovative psychotherapy approach and breaks new ground in the field of psychotherapy research for psychosis.
Tracking Information
- NCT #
- NCT04874974
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Susanne Lucae, MD, Prof. Max-Planck-Institute of Psychiatry Principal Investigator: Johannes M Kopf-Beck, PhD Max-Planck-Institute of Psychiatry
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