The Effect of Tobacco Products on Wound Healing
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Smoking
- Tobacco Smoking
- Tobacco Use
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
Participants will be recruited from ongoing studies will some recruitment of tobacco users and non-smoking controls outside of ongoing studies. In this prospective, cohort study of various tobacco users and non-smokers, a punch biopsy model of wound healing will be used to determine the effects of v...
Participants will be recruited from ongoing studies will some recruitment of tobacco users and non-smoking controls outside of ongoing studies. In this prospective, cohort study of various tobacco users and non-smokers, a punch biopsy model of wound healing will be used to determine the effects of various tobacco products on inflammatory response and oxidative stress response to wounding: Clinical wound inflammation as assessed by: Thermography, Clinical assessment, Laser Doppler Technologies, Transcutaneous oxygen assessment Biological wound inflammation as assessed by: Cytokine profiles, Histology, Genetic assessment, Epigenetic evaluation Systemic inflammation as assessed by: Biomarkers, Cell counts
Tracking Information
- NCT #
- NCT04870970
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Dorothy Hatsukami, PhD University of Minnesota
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