Opioid Modulation and Neural Reward Activation in Healthy Adults
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Alcohol Drinking
- Opioid Use, Unspecified
- Type
- Interventional
- Phase
- Phase 1Phase 2
- Design
- Allocation: RandomizedIntervention Model: Crossover AssignmentIntervention Model Description: Participants will be counterbalanced for the order they undergo placebo and medication.Masking: Triple (Participant, Investigator, Outcomes Assessor)Masking Description: capsule, double blindPrimary Purpose: Basic Science
Participation Requirements
- Age
- Between 18 years and 35 years
- Gender
- Both males and females
Description
The study will employ a crossover design. The study will use the monetary incentive delay task during functional MRI to assess reward. This task presents participants with cues indicating whether they are playing to win $5, win $0, or to avoid losing $5. This task has been well-validated to elicit a...
The study will employ a crossover design. The study will use the monetary incentive delay task during functional MRI to assess reward. This task presents participants with cues indicating whether they are playing to win $5, win $0, or to avoid losing $5. This task has been well-validated to elicit activation in a key reward response area of the brain called the ventral striatum.
Tracking Information
- NCT #
- NCT04854551
- Collaborators
- Not Provided
- Investigators
- Not Provided
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