MRI-guided Lateral Lymph Node Dissection in Rectal Cancer
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Rectal Cancer
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 75 years
- Gender
- Both males and females
Description
Our study design is a multicenter, prospective, registry study. We would enroll 268 patients with lower rectal cancer whose preoperative MRI showed laterally lymph node diameter ? 5mm. The postoperative adjuvant chemoradiotherapy is determined by the pathological results. For patients of stage II an...
Our study design is a multicenter, prospective, registry study. We would enroll 268 patients with lower rectal cancer whose preoperative MRI showed laterally lymph node diameter ? 5mm. The postoperative adjuvant chemoradiotherapy is determined by the pathological results. For patients of stage II and patients of stage III with unfavorable histologic features, six months of adjuvant chemotherapy of fluorouracil-based regimen with radiotherapy of 45.0 ~ 50.5 Gy are recommended. The postoperative examination should be performed every three months in the first two years and every six months in the following three years. Our study is expected to last five years, of which two years for recruiting patients, three years for follow-up.
Tracking Information
- NCT #
- NCT04850027
- Collaborators
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
- Shengjing Hospital
- West China Hospital
- The First Affiliated Hospital of Dalian Medical University
- China-Japan Friendship Hospital
- Tianjin People's Hospital
- Peking University First Hospital
- Beijing Friendship Hospital
- Second Affiliated Hospital of Suzhou University
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- Beijing Cancer Hospital
- Shanghai Cancer Hospital, China
- The First Hospital of Jilin University
- Zhejiang Cancer Hospital
- China-Japan Union Hospital, Jilin University
- Peking Union Medical College Hospital
- The Affiliated Hospital of Xuzhou Medical University
- The Affiliated Hospital of Qingdao University
- Ruijin Hospital
- Chinese PLA General Hospital
- First Hospital of China Medical University
- Investigators
- Principal Investigator: Qian Liu, M.D. Cancer Institute and Hospital, Chinese Academy of Medical Sciences