Ultrasound-Assessed Diaphragmatic Dysfunction as a Predictor of Weaning Outcome
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Sepsis
- Weaning Failure
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 60 years
- Gender
- Both males and females
Description
After being informed about the study and giving written informed consent, Intubated and mechanically ventilated patients with sepsis on admission and fulfilling criteria of weaning from mechanical ventilation (MV), will undergo diaphragm ultrasound during spontaneous breathing trial on T-piece. We w...
After being informed about the study and giving written informed consent, Intubated and mechanically ventilated patients with sepsis on admission and fulfilling criteria of weaning from mechanical ventilation (MV), will undergo diaphragm ultrasound during spontaneous breathing trial on T-piece. We will measure diaphragm excursion (DE), diaphragm thickness (DT) and calculate diaphragm thickness fraction (DTF): DT during inspiration - DT during expiration / DT during expiration According to weaning outcome, patients will be divided into 2 groups: Successful weaning group Weaning failure group By statistical analysis we will define the cut off value and area under curve (AUC) for DE and DTF and we can confirm if DE and DTF using ultrasound can be used as predictors for weaning from MV or not
Tracking Information
- NCT #
- NCT04825509
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Mohamed Saad Ain Shams University