One Year Follow-up After Rescuscited Cardiac Arrest

Summary

Participation Requirements

Description

Patients older than 18 years old undergoing CA for cardiac arrest discharged alive from hospital will be included from January 1, 2018 to May 31, 2020. The investigators exclude all the patients who died during the in-hospital stay and patients who had VF immediately rescucitated by electric cardiov...

Patients older than 18 years old undergoing CA for cardiac arrest discharged alive from hospital will be included from January 1, 2018 to May 31, 2020. The investigators exclude all the patients who died during the in-hospital stay and patients who had VF immediately rescucitated by electric cardioversion including only unconscious patients at admission in the cath lab. Patients were also excluded if they did not receive active in-hospital treatment after cardiac arrest based on either a do-not-attempt-resuscitation order, end-stage malignancy preceding the arrest, or had minimal chances of meaningful survival (defined as not witnessed cardiac arrest with asystole, lengthy resuscitation, or advanced age). Patient characteristics, modalities of cardiac arrest and intra-hospital progress were collected using DxCare software. Cardiac and neurological status will be collected at 1 year follow-up either by using consultation report or by a phone call If available, an initial evaluation is done at 3 months. Cerebral Performance Category (CPC) will be used to assess the neurological functional status Primary end point is the rate of patients with severe neurological sequelae at one year follow-up defined as CPC category ? 3. Secondary ends points will evaluate the survival rate, NYHA functional class, rehospitalization and quality of life at 1 year. Quality of life at one year is recorded using the QOLIBRI (Quality of Life after Brain Injury) which is a novel health-related quality-of-life (HRQoL) instrument specifically developed for traumatic brain injury (TBI) (2). It provides a profile of HRQoL in six domains together with an overall score. The questionnaire is completed by asking questions by phone to patients available at 1 year follow-up. The inclusion of 96 patients will make possible to highlight a frequency of severe neurological sequelae of 10 percent with a precision of 5 percent (width of the confidence interval) and considering an alpha risk of 5 percent. Considering that our active patient file include 150 cardiac arrests per year, of which 50 are discharged alive per year, the inclusion of 96 patients discharged alive from hospital over a 2-year period seems to be realistic.

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