Modulation of Endothelial Dysfonction Using Vitamin C in Septic Shock Patients
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Septic Shock
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Cross-Sectional
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
This is a transversal study allowing to compare the microcirculatory reactivity before and after a 30-minute intravenous infusion of 40 mg/kg vitamin C. Design: • A monocentric, open-label, transversal study Sample size : 30 patients Assessement: Between 6 hours and 24 hours after admission, the pat...
This is a transversal study allowing to compare the microcirculatory reactivity before and after a 30-minute intravenous infusion of 40 mg/kg vitamin C. Design: • A monocentric, open-label, transversal study Sample size : 30 patients Assessement: Between 6 hours and 24 hours after admission, the patient will be included after collection of the non opposition. There will be two evaluation times: T0 before the start of vitamin C's perfusion, and T1: 1 hour after the end. No interim analysis is planned. Analysis will be performed at the end of the study after data review and freezing of data base.
Tracking Information
- NCT #
- NCT04778605
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Hafid AIT-OUFELLA, Professor Assistance Publique - Hôpitaux de Paris
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