Recruitment

Recruitment Status
Active, not recruiting

Inclusion Criteria

Transfer at least one high quality frozen embryo;
Diagnosed with adenomyosis by ultrasound
Patients agreed to use low molecular weight heparin after FET, and they were able to sign informed consent in person.
...
Transfer at least one high quality frozen embryo;
Diagnosed with adenomyosis by ultrasound
Patients agreed to use low molecular weight heparin after FET, and they were able to sign informed consent in person.
The first frozen thawed embryo transfer cycle, by hormone replacement protocol
The basal serum level of FSH was less than 10 IU / L

Exclusion Criteria

There were contraindications to hormone replacement therapy and low molecular weight heparin;
With abnormal karyotype;
Unable to follow-up
...
There were contraindications to hormone replacement therapy and low molecular weight heparin;
With abnormal karyotype;
Unable to follow-up
PCOS, RIF patients;
Participating in other clinical studies;
There are indications of conventional anticoagulation or antiplatelet therapy, such as antiphospholipid syndrome, autoimmune diseases, coagulation dysfunction, etc;
Accompanied with other uterine diseases: intrauterine adhesion, intramural myoma, moderate to severe endometriosis, congenital uterine malformation, endometrial tuberculosis, thin endometrium < 8mm on the day of transformation, etc;

Summary

Conditions
  • Adenomyosis
  • Assisted Reproductive Technology
Type
Interventional
Design
  • Allocation: Randomized
  • Intervention Model: Parallel Assignment
  • Masking: Double (Participant, Care Provider)
  • Primary Purpose: Treatment

Participation Requirements

Age
Between 20 years and 38 years
Gender
Only females

Inclusion Criteria

Transfer at least one high quality frozen embryo;
Diagnosed with adenomyosis by ultrasound
Patients agreed to use low molecular weight heparin after FET, and they were able to sign informed consent in person.
...
Transfer at least one high quality frozen embryo;
Diagnosed with adenomyosis by ultrasound
Patients agreed to use low molecular weight heparin after FET, and they were able to sign informed consent in person.
The first frozen thawed embryo transfer cycle, by hormone replacement protocol
The basal serum level of FSH was less than 10 IU / L

Exclusion Criteria

There were contraindications to hormone replacement therapy and low molecular weight heparin;
With abnormal karyotype;
Unable to follow-up
...
There were contraindications to hormone replacement therapy and low molecular weight heparin;
With abnormal karyotype;
Unable to follow-up
PCOS, RIF patients;
Participating in other clinical studies;
There are indications of conventional anticoagulation or antiplatelet therapy, such as antiphospholipid syndrome, autoimmune diseases, coagulation dysfunction, etc;
Accompanied with other uterine diseases: intrauterine adhesion, intramural myoma, moderate to severe endometriosis, congenital uterine malformation, endometrial tuberculosis, thin endometrium < 8mm on the day of transformation, etc;

Locations

Nanjing, Jiangsu, 210008
Nanjing, Jiangsu, 210008

Tracking Information

NCT #
NCT04741295
Collaborators
Not Provided
Investigators
Not Provided