Interval Between Neoadjuvant Therapy and Surgery in the Treatment of Locally Advanced Rectal Cancer (CRONOS)
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
Summary
- Conditions
- Neoadjuvant Therapy
- Rectal Cancer
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Retrospective
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
In the treatment of locally advanced rectal cancer, an optimal interval between neoadjuvant therapy and surgery might improve oncological outcomes. Besides, those patients who achieve a good response might benefit from active surveillance, avoiding surgical comorbidities. This optimal interval is ye...
In the treatment of locally advanced rectal cancer, an optimal interval between neoadjuvant therapy and surgery might improve oncological outcomes. Besides, those patients who achieve a good response might benefit from active surveillance, avoiding surgical comorbidities. This optimal interval is yet to be defined. This study will aim to better define the role of time interval between the end of neoadjuvant therapy (NAT) and TME in Spanish regions, together with analyzing the importance of restaging MRI and define the basis for implementing a "watch and wait" protocol.
Tracking Information
- NCT #
- NCT04717947
- Collaborators
- Complejo Hospitalario Universitario de Santiago
- Hospital Universitario Marqués de Valdecilla
- Hospital de Sant Joan Despí Moisès Broggi
- Hospital del Mar
- Hospital Son Espases
- Hospital Universitario La Fe
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
- Fundacion del Hospital Nacional de Paraplejicos para la Investigacion y la Integracion
- Investigators
- Study Director: Antonio Lacy, PhD Hospital Clinic of Barcelona
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