rTMS on Appetite and Cognitive Function in Schizophrenia
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Schizophrenia
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: 60 participants are randomized, through the predetermined random number list, into intervention group or sham stimulation group in equal.Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)Primary Purpose: Prevention
Participation Requirements
- Age
- Between 18 years and 40 years
- Gender
- Both males and females
Description
The weight gain and metabolic dysfunction has been vital conditions for individuals with schizophrenia. The cognitive function deficit has also been a major symptom for schizophrenia. However, metabolic dysfunction could further impair the cognition. rTMS is a promising novel intervention, which hav...
The weight gain and metabolic dysfunction has been vital conditions for individuals with schizophrenia. The cognitive function deficit has also been a major symptom for schizophrenia. However, metabolic dysfunction could further impair the cognition. rTMS is a promising novel intervention, which have strong potentials on moderating increased appetite and cognitive deficits in schizophrenia, as it has been proved for the treatment of depression. Therefore, the investigators designed this randomized controlled clinical trial to evaluate the efficacy and safety of rTMS, using iTBS pattern, on prevention of the elevated appetite and cognitive deficiency in individual with schizophrenia. The intervention will last for ten continuous days and the follow-ups are scheduled at baseline, 10days and 30days. The primary outcomes include the change of MCCB score, AEBQ score and EEG data. Secondary outcomes include the change of serum metabolic indexes and anthropometry indexes.
Tracking Information
- NCT #
- NCT04714970
- Collaborators
- Shanghai Mental Health Center
- Investigators
- Principal Investigator: Renrong Wu, Prof Central South University Psychiatry Department
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