Recruitment

Recruitment Status
Not yet recruiting
Estimated Enrollment
Same as current

Summary

Conditions
  • Alzheimer Disease
  • Sleep
Type
Interventional
Phase
Phase 2
Design
Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)Primary Purpose: Prevention

Participation Requirements

Age
Between 65 years and 125 years
Gender
Both males and females

Description

This study will investigate if long-term treatment with suvorexant will slow amyloid-? accumulation in the brain. Amyloid-? is a protein involved in the disease process leading to Alzheimer's disease. This study will evaluate if suvorexant can decrease the amount of amyloid-beta detected on brain sc...

This study will investigate if long-term treatment with suvorexant will slow amyloid-? accumulation in the brain. Amyloid-? is a protein involved in the disease process leading to Alzheimer's disease. This study will evaluate if suvorexant can decrease the amount of amyloid-beta detected on brain scans (primary outcome).

Tracking Information

NCT #
NCT04629547
Collaborators
Not Provided
Investigators
Principal Investigator: Brendan Lucey, MD Washington Univeristy School of Medicine