Acutelines: a Large Data-/Biobank of Acute and Emergency Medicine
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Electrolyte Disturbance
- Acute Disease
- Acute Kidney Injury
- Anaphylaxis
- Complication of Treatment
- Pulmonary Embolism
- Shock
- Dyspnea
- Emergencies
- Frailty
- Urinary Tract Infections
- Polypharmacy
- Hemorrhage
- Intoxication by Drug
- Skin Infection
- Pneumonia
- Sepsis
- Thrombosis
- Syncope
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
Acutelines is a prospective biobank including patients with a broad spectrum of acute conditions. Its aim is to facilitate interdisciplinary research on the etiology and development of acute diseases with the aid of systematically collected biomaterials and medical data over various timepoints, both...
Acutelines is a prospective biobank including patients with a broad spectrum of acute conditions. Its aim is to facilitate interdisciplinary research on the etiology and development of acute diseases with the aid of systematically collected biomaterials and medical data over various timepoints, both during the course of the patient's disease and after recovery. Clinical data, imaging data and biomaterial (i.e. blood, urine, feces, hair) are collected for patients presenting to the Emergency Department (ED) with a broad range of acute disease presentations. A deferred consent procedure (by proxy), is in place to allow collecting data and biomaterials prior to obtaining written consent. The digital infrastructure in place and the software used ensures automated capturing of all bed-side monitoring data (i.e. electrophysiological waveforms, vital parameters), and the secure importation of data from other sources, such as the electronic health records of the hospital, ambulance and general practitioner, municipal registration, health insurance companies and pharmacy. Follow up data are collected for all included patients during the first 72-hours of their hospitalization and 3-months, 1-year, 2-years and 5 years after their ED visit. Data and materials to be collected includes: Demographic and health data (i.e. [experiences] health, quality of life, functional status) Medical history (i.e. co-morbidity, intoxications, medication use) Admission reason to emergency department Physical examination and vital parameters Clinical diagnostic data (i.e. [point-of-care] ultrasound, X-ray, CT-scan, laboratory results) Electrophysiological waveforms (i.e. electrocardiogram [ECG], plethysmography) Biomaterials Treatment (i.e. medication use, non-pharmacological treatment, treatment decisions, length-of-stay in hospital, admission to intensive care unit [ICU])
Tracking Information
- NCT #
- NCT04615065
- Collaborators
- Not Provided
- Investigators
- Study Director: Ewoud ter Avest, MD, PhD University Medical Center Groningen Study Director: Jan ter Maaten, MD, PhD University Medical Center Groningen Study Chair: Barbara van Munster, MD, PhD University Medical Center Groningen Principal Investigator: Hjalmar Bouma, MD, PhD University Medical Center Groningen