Diabetic Retinopathy as a Marker of Cognitive Dysfunction and Depression
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Cognitive Dysfunction
- Cognitive Impairment
- Depression
- Diabetic Retinopathy
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Cross-Sectional
Participation Requirements
- Age
- Between 65 years and 125 years
- Gender
- Both males and females
Description
A cross sectional study will be performed to determine correlation between retinal endpoints in persons with type 2 diabetes and cognitive impairment. 200 patients with type 2 diabetes without diabetic retinopathy and non to severe diabetic retinopathy. Primary objective: To determine whether struct...
A cross sectional study will be performed to determine correlation between retinal endpoints in persons with type 2 diabetes and cognitive impairment. 200 patients with type 2 diabetes without diabetic retinopathy and non to severe diabetic retinopathy. Primary objective: To determine whether structural and/or metabolic retinal markers are able to differentiate people with minimal cognitive impairment (MCI) within persons with type 2 diabetes (T2D). Secondary objective To assess whether retinal metabolism measured by oximetry can identify individuals with MCI among people with T2D. To assess whether retinal metabolism measured by oximetry can identify individuals with depressive symptoms among people with T2D. To determine whether retinal structural markers can identify people with depressive symptoms among people with T2D.
Tracking Information
- NCT #
- NCT04610749
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Frederik N Pedersen, M.D Department of Ophthalmology, OUH