Esophageal Cancer Risk Identification Based on Opportunistic Screening?ECRIOS?

Summary

Participation Requirements

Description

Esophageal cancer is one of the most unknown and deadiest cancers worldwide, mainly because of its extremely aggressive nature and poor survival rate. In 2018, the incidence rate and mortality rate of esophageal cancer were 6.3/100000 and 5.5/100000. There are clear differences between the risk fact...

Esophageal cancer is one of the most unknown and deadiest cancers worldwide, mainly because of its extremely aggressive nature and poor survival rate. In 2018, the incidence rate and mortality rate of esophageal cancer were 6.3/100000 and 5.5/100000. There are clear differences between the risk factors of both histological types that affect their incidence and distribution worldwide.There are areas of high incidence of squamous cell carcinoma (some areas in China) that meet the requirements for cost-effectiveness of endoscopy for early diagnosis in the general population of those areas. The gold standard to detect and diagnose esophageal cancer is upper gastrointestinal endoscopy with biopsy. However, China is a country with large population, which makes it difficult to perform screening endoscopy in the whole crowd. There are several researches showing that there is a low detecting rate of esophageal cancer if only perform screening endoscopy in high risk area. This multicenter study aims to propose a table, including Risk factors for esophageal cancer. Besides, esophageal cytology is essential to detect and diagnose esophageal. Now there are improved esophageal cell collector?CytospongeTM?EsophaCapTM?which adopt an inflatable sponge capsule design to increase the contact area with the esophageal mucosa. Our study aims to evaluate the function and value of new type esophageal cell collector to China's esophageal cancer screening.

Tracking Information