FoxBioNet: ECV (Extracellular Vesicle) 004
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Parkinson Disease
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Cross-Sectional
Participation Requirements
- Age
- Between 30 years and 125 years
- Gender
- Both males and females
Description
Specific aims of this project are: Primary Objectives: To evaluate each assay performance for its ability to detect LRRK2, its activity and/or the detection and activity of the pathways it impacts using a variety of different approaches (quantitative western blot, immunoassays and LC-MS). Assay perf...
Specific aims of this project are: Primary Objectives: To evaluate each assay performance for its ability to detect LRRK2, its activity and/or the detection and activity of the pathways it impacts using a variety of different approaches (quantitative western blot, immunoassays and LC-MS). Assay performance will be assessed and those demonstrating high sensitivity and consistency will be considered for further development. Secondary Objectives: To assess the ability of the assay or a combination of assays to differentiate pathogenic LRRK2 variant manifesting and non-manifesting carriers, idiopathic PD and healthy non-carriers.
Tracking Information
- NCT #
- NCT04603326
- Collaborators
- Indiana University
- Clinical Trials Coordination Center
- University Health Network, Toronto
- Investigators
- Not Provided
Get Well Soon