Periodic Limb Movement Syndrome in Patients With Cerebral Small Vessel Disease.

Periodic Limb Movement Syndrome in Patients With Cerebral Small Vessel Disease: a Clinical and Neuropsychological Study.

Patients from 60 to 75 years old diagnosed with cerebral small vessel disease with no history of symptomatic stroke, brain tumor, traumatic brain injury, seizures and neurodegenerative or mental disorder will undergo overnight leg actigraphy and cardiorespiratory monitoring. Those of them with apnea/hypopnea index under 5 will be enrolled. Brain MRI and cognitive assessment will be performed at baseline and in 1-year follow-up, sleep quality will be assessed at baseline with self-reported questionnaires. Progression of cerebral small vessel disease markers and cognitive dysfunction will be compared between patients with high periodic limb movement index (the number of periodic limb movement ? 15 per hour of sleep) and controls (periodic limb movement index < 15/h).

Periodic Limb Movement Syndrome in Patients With Cerebral Small Vessel Disease.

Recruitment

Summary

Participation Requirements

Description

Tracking Information