Comparing Chemotherapy With/Without Toripalimab For Primary Metastatic Nasopharyngeal Carcinoma
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Nasopharyngeal Carcinoma
- Type
- Interventional
- Phase
- Phase 2
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 70 years
- Gender
- Both males and females
Description
About 4-10% of patients with nasopharyngeal carcinoma (NPC) have metastatic disease at diagnosis. The treatment recommendation of primary metastatic NPC is systemic chemotherapy. However, the optimal regimen is yet to determine due to lack of prospective randomized trial for this unique group of pat...
About 4-10% of patients with nasopharyngeal carcinoma (NPC) have metastatic disease at diagnosis. The treatment recommendation of primary metastatic NPC is systemic chemotherapy. However, the optimal regimen is yet to determine due to lack of prospective randomized trial for this unique group of patients. Generally, GP regimen is used as the first-line treatment of primary metastatic NPC. The aim of this study is to compare the efficacy of Toripalimab Combined with GP Regimen Chemotherapy Versus GP Regimen Chemotherapy for Primary Metastatic NPC.
Tracking Information
- NCT #
- NCT04517214
- Collaborators
- Sir Run Run Shaw Hospital
- Fudan University Eye and ENT Hospital
- Anhui Provincial Hospital
- Hangzhou Cancer Hospital
- Ningbo Medical Center Lihuili Hospital
- The First People's Hospital of Changzhou
- Cancer Hospital of Chinese Academy of Medical Science, Shenzhen Center
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
- Nanfang Hospital of Southern Medical University
- Shenzhen People's Hospital
- Guangzhou Panyu Central Hospital
- First Affiliated Hospital of Xi'anJiaotong Univerisity
- Investigators
- Study Director: Xiaomin Ou, M.D. Fudan University
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