Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- ALI
- ARDS, Human
- COVID-19
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Between 16 years and 90 years
- Gender
- Both males and females
Description
EBP will be measured on 100 patients with COVID-19 positive patients. Measurement will be done on daily bases from the time the patient is treated as" in patients" until discharge or to the transition to ICU care and initiation of mechanical ventilation to follow the EBP pattern over time course of ...
EBP will be measured on 100 patients with COVID-19 positive patients. Measurement will be done on daily bases from the time the patient is treated as" in patients" until discharge or to the transition to ICU care and initiation of mechanical ventilation to follow the EBP pattern over time course of the disease. EBP measurements will also be done on 100 patients without COVID19 infection with normal lung function as a control cohort. Measurements on patients with mechanical ventilation in the ICU. To reduce the need of invasive diagnostics and in hospital transportation for diagnostics with a high risk of infecting other patients and staff in the environment, but also to measure the extent of lung injury over time, EBP will be measured at daily bases to follow the EBP pattern on patients in mechanical ventilation. Preclinical studies have shown that EBP can measure the extent of lung injury over time (onset of ARDS and recovery (unpublished data)) Method: EBP will be measured on 100 patients in mechanical ventilation at the intensive care on daily bases to follow the EBP pattern over time. Measurements will be done on patients in mechanical ventilation on ECMO (extra corporal membrane oxygenation) support.
Tracking Information
- NCT #
- NCT04503057
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Sandra Lindstedt Ingemansson, MD, PhD Region Skåne, Lund University