Plaque mOrphology iMpact on Side Branch Occlusion at oPtical Coherence Tomography Evaluation in Percutaneous Coronary Interventions
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Bifurcation
- Percutaneous Coronary Intervention
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Between 21 years and 99 years
- Gender
- Both males and females
Description
We hypothesized that in bifurcation lesion treatment, morphology of the plaque located in the main vessel may impact on the risk of developing SBO. The objectives of POMPEI study as follows: Primary objective: To identify correlation between lipid volume content of MV plaque and risk of SBO (TIMI fl...
We hypothesized that in bifurcation lesion treatment, morphology of the plaque located in the main vessel may impact on the risk of developing SBO. The objectives of POMPEI study as follows: Primary objective: To identify correlation between lipid volume content of MV plaque and risk of SBO (TIMI flow<3) Secondary objectives: To identify the plaque morphology characteristics associated with SBO in patients undergoing bifurcation PCI. OCT parameters which will be assessed include: distribution of lipid volume and lipid arc in the MV and around SB ostium before and after stenting; prevalence of healed plaque rupture and erosion and its correlation with SBO; correlation between calcium distribution within the plaque and SBO; correlation between bifurcation angle and SBO; and correlation between angiographic images of haziness at SB ostium and OCT findings. To determine the prevalence of significant SB ostium stenosis in patients undergoing bifurcation PCI. To determine the incidences of SBO following bifurcation PCI. To determine the incidence and extent of peri-procedural myocardial injury and infarction following bifurcation PCI. To determine correlation between SB lesion extension from the ostium and SBO
Tracking Information
- NCT #
- NCT04501549
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Chin Chee Yang, MD National Heart Centre Singapore