Characterization of Cerebral Tau Aggregates With 18F-RO6958948 PET in the ALFA Population
Last updated on July 2021Recruitment
- Recruitment Status
- Enrolling by invitation
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Healthy
- Mild Cognitive Impairment
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Other
Participation Requirements
- Age
- Between 45 years and 125 years
- Gender
- Both males and females
Description
CROSS-SECTIONAL OBJECTIVES To measure 18F-RO6958948 retention in selected participants of ALFA-related studies as a function of amyloid levels. To study the relation between 18F-RO6958948 retention and amyloid levels. To characterize imaging correlates as a function of tau and amyloid levels. To stu...
CROSS-SECTIONAL OBJECTIVES To measure 18F-RO6958948 retention in selected participants of ALFA-related studies as a function of amyloid levels. To study the relation between 18F-RO6958948 retention and amyloid levels. To characterize imaging correlates as a function of tau and amyloid levels. To study the role of tau retention on cognitive performance. To define predictors of tau retention. LONGITUDINAL OBJECTIVES To measure tau accumulation and spreading in participants of the ALFA-related studies of BBRC as a function of baseline amyloid levels. To study the dynamic relation between tau spreading and amyloid levels longitudinally. To define predictors of tau spreading.
Tracking Information
- NCT #
- NCT04482660
- Collaborators
- Hoffmann-La Roche
- Hospital Clinic of Barcelona
- Investigators
- Not Provided
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