Clinical Trial Intelligent Biometrics for PTSD - Clinical Trial

Summary

Participation Requirements

Description

Posttraumatic stress disorder (PTSD) is a chronic and debilitating psychiatric condition. Prolonged Exposure (PE) therapy is an effective, evidence-based treatment for PTSD; however, approximately one-quarter of patients drop out prematurely and one-third who do complete treatment remain symptomatic...

Posttraumatic stress disorder (PTSD) is a chronic and debilitating psychiatric condition. Prolonged Exposure (PE) therapy is an effective, evidence-based treatment for PTSD; however, approximately one-quarter of patients drop out prematurely and one-third who do complete treatment remain symptomatic. The proposed study will employ a randomized clinical trial (N=40 treatment-seeking veterans with current PTSD) to evaluate the acceptability and preliminary efficacy of IB-PE and investigate predictors of outcome by accomplishing the following milestones: (1a) Evaluate ability of IB-PE (therapist guided vs. record only) in reducing PTSD severity from baseline to end of treatment; and (2b) Use a variety of in vivo exposures (IVEs) to identify biometric and behavioral indicators (high heart rate, skin conductance) with high predictive value of treatment response. We will use a system of discrete wearables (camera, microphone) to allow the therapist to accompany a participant on an IVE (e.g: walk through a crowded building). The system will pair with a cellular application, and will record information such as heart rate and skin conductance. This system will also allow the participant to communicate with the study therapist during this guided exercise.

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