AIM to Improve Asthma: Airflow Improvements During Meal-Prep
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Asthma in Children
- Pollution Exposure
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: This is a parallel trial with two groups, where one group receives the intervention following one week of baseline data collection. The other group will receive the intervention after a delay (one week later).Masking: None (Open Label)Masking Description: Participants and field staff can not be masked to the intervention, however the data analysts will be masked.Primary Purpose: Prevention
Participation Requirements
- Age
- Between 6 years and 12 years
- Gender
- Both males and females
Description
In this trial of 60 children ages 6-12 with asthma, the investigators will randomize 30 children and their households to receive an intensive home kitchen ventilation intervention after one week of baseline data collection and the other 30 to receive the intervention after two weeks of baseline data...
In this trial of 60 children ages 6-12 with asthma, the investigators will randomize 30 children and their households to receive an intensive home kitchen ventilation intervention after one week of baseline data collection and the other 30 to receive the intervention after two weeks of baseline data collection. This design will allow for analysis as both a randomized controlled trial, and as a before/after trial, allowing for the benefits of both designs. The intervention includes education regarding improving ventilation in their homes during cooking and replacement of their range hood if it has inadequate flow or an intolerable noise level. During baseline data collection periods the households will be encouraged to continue their regular cooking patterns. The investigators will measure home particulate matter <2.5 microns (PM2.5) and nitrogen dioxide (NO2) levels for one week at baseline, one week after 30 families have received the intervention and a final week after all remaining families receive the cooking ventilation intervention, to assess for changes within each household as well as between groups. The investigators will also examine changes in airways inflammation (as measured by the exhaled fraction of nitric oxide, FeNO), lung function (as measured by spirometry), reported symptoms, and asthma quality of life after the baseline and each intervention period. Members of the research team have successfully conducted youth participatory action research in the low-income, high asthma prevalence community of Richmond, California (CA) as well as extensive youth participatory action research on other environmental health concerns in the low income city of Salinas, CA; using a similar model, the investigators aim to teach research methods to a new group of Richmond youth.
Tracking Information
- NCT #
- NCT04464720
- Collaborators
- National Institute of Environmental Health Sciences (NIEHS)
- Investigators
- Principal Investigator: John R Balmes, MD University of California, Berkeley
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