Intestinal Inflammation in CF Patients
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Cystic Fibrosis
- Cystic Fibrosis Gastrointestinal Disease
- Cystic Fibrosis in Children
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 10 years and 125 years
- Gender
- Both males and females
Description
The aim is to determine the prevalence of intestinal inflammation by measurement of fecal calprotectin and/or histological evaluation of intestinal tissue biopsies in both pediatric and adult CF populations. Pediatric CF population (Age 10-18 years): Determine the prevalence of intestinal inflammati...
The aim is to determine the prevalence of intestinal inflammation by measurement of fecal calprotectin and/or histological evaluation of intestinal tissue biopsies in both pediatric and adult CF populations. Pediatric CF population (Age 10-18 years): Determine the prevalence of intestinal inflammation in a cohort of pediatric CF patients based on fecal calprotectin levels in stool samples. Assess the correlation between fecal calprotectin and abdominal symptoms/QOL. Adult CF population (Age ? 18 years): Determine the prevalence of intestinal inflammation in a cohort of adult CF patients based on histological evaluation of intestinal tissues biopsies and fecal calprotectin levels in stool samples in adult CF patients who have not undergone lung or liver transplantation. in adult CF patients who have undergone lung or liver transplantation. Assess the correlation between fecal calprotectin and histological-proven intestinal inflammation in adult CF patients. Assess the correlation between histological-proven intestinal inflammation and abdominal symptoms/QOL as well as the correlation between fecal calprotectin and abdominal symptoms/QOL.
Tracking Information
- NCT #
- NCT04392544
- Collaborators
- Cystic Fibrosis Canada
- Investigators
- Principal Investigator: Tanja Gonska, MD The Hospital for Sick Children
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