ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Amyotrophic Lateral Sclerosis
- Behavioral Variant Frontotemporal Dementia (bvFTD)
- Semantic Variant Primary Progressive Aphasia (svPPA)
- C9orf72
- Corticobasal Degeneration (CBD)
- Progressive Supranuclear Palsy (PSP)
- Frontotemporal Lobar Degeneration (FTLD)
- FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)
- GRN Related Frontotemporal Dementia
- MAPT Gene Mutation
- TBK1 Gene Mutation
- Nonfluent Variant Primary Progressive Aphasia (nfvPPA)
- Oligosymptomatic Progressive Supranuclear Palsy
- Oligosymptomatic PSP (oPSP)
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
The ARTFL LEFFTDS Longitudinal Frontotemporal Dementia (ALLFTD) study aims to evaluate sporadic (s-) and familial (f-) frontotemporal lobar degeneration (FTLD) patients and asymptomatic family members of f-FTLD patients, characterizing the cohorts longitudinally and informing clinical trial design. ...
The ARTFL LEFFTDS Longitudinal Frontotemporal Dementia (ALLFTD) study aims to evaluate sporadic (s-) and familial (f-) frontotemporal lobar degeneration (FTLD) patients and asymptomatic family members of f-FTLD patients, characterizing the cohorts longitudinally and informing clinical trial design. The study has two arms: a "longitudinal arm" involving a comprehensive assessment of clinical, functional, imaging, and biofluid data collection annually, and a "biofluid-focused arm" involving limited clinical data to accompany biospecimen collection. For more information: https://www.allftd.org/
Tracking Information
- NCT #
- NCT04363684
- Collaborators
- University of California, San Francisco
- National Institute on Aging (NIA)
- National Institute of Neurological Disorders and Stroke (NINDS)
- Investigators
- Principal Investigator: Bradley Boeve, MD Mayo Clinic Principal Investigator: Adam Boxer, MD, PhD University of California, San Francisco Principal Investigator: Howie Rosen, MD University of California, San Francisco
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