Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
Same as current

Summary

Conditions
  • Cerebral Palsy
  • Epilepsy
  • Hypoxic Ischemic Encephalopathy
  • Intellectual Disability
  • Intracranial Hemorrhages
  • Neonatal Seizure
  • Stroke
Design
Observational Model: CohortTime Perspective: Prospective

Participation Requirements

Age
Between 2 years and 8 years
Gender
Both males and females

Description

Neonatal seizures due to brain injury (acute symptomatic seizures) are associated with high risk of neurodevelopmental disability in infancy. Although prognosis in early childhood is a critical question for parents and providers, outcomes beyond infancy are largely unknown. Further, parents of infan...

Neonatal seizures due to brain injury (acute symptomatic seizures) are associated with high risk of neurodevelopmental disability in infancy. Although prognosis in early childhood is a critical question for parents and providers, outcomes beyond infancy are largely unknown. Further, parents of infants with neonatal seizures are at risk for mental health disorders, which can undermine their ability to care for a child with medical complexity and may contribute to impaired child development. The NSR-DEV study is a longitudinal cohort study of around 280 Neonatal Seizure Registry participants enrolled at one of nine sites across the USA. Participants will be evaluated using developmental questionnaires and in-person neurodevelopmental testing. Parent well-being will be assessed at each time point.

Tracking Information

NCT #
NCT04337697
Collaborators
  • University of Michigan
  • Stanford University
  • Duke University
  • Boston Children's Hospital
  • Children's National Research Institute
  • Massachusetts General Hospital
  • Children's Hospital of Philadelphia
  • Children's Hospital Medical Center, Cincinnati
  • National Institute of Neurological Disorders and Stroke (NINDS)
Investigators
Principal Investigator: Hannah C. Glass, MDCM, MAS University of California, San Francisco