Diagnostic Evaluation of Urine DNA Methylation/Somatic Mutation Profiling for the Detection of Urothelial Carcinoma
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Bladder Cancer
- Urothelial Carcinoma
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
This is a prospective study that involves 11 centers in China and 1200 participants. The assay analyzes the DNA methylation/somatic mutation profiles of bladder cancer-specific biomarkers non-invasively using urine specimens collected before invasive diagnosis/treatment. The performance characterist...
This is a prospective study that involves 11 centers in China and 1200 participants. The assay analyzes the DNA methylation/somatic mutation profiles of bladder cancer-specific biomarkers non-invasively using urine specimens collected before invasive diagnosis/treatment. The performance characteristics(sensitivity and specificity) of the assay for detection of urothelial carcinoma is evaluated in comparison to pathology or cystoscopy.
Tracking Information
- NCT #
- NCT04314245
- Collaborators
- West China Hospital
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
- RenJi Hospital
- Tongji Hospital
- Peking University People's Hospital
- First Affiliated Hospital Xi'an Jiaotong University
- The First Affiliated Hospital with Nanjing Medical University
- Southern Medical University, China
- Nanfang Hospital of Southern Medical University
- Sichuan Cancer Hospital and Research Institute
- Affiliated Hospital & Clinical Medical College of Chengdu University
- Investigators
- Study Chair: Jian HUANG, MD Sun Yat-sen Memorial Hospital,Sun Yat-sen University
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