Metabolic and Bio-behavioral Effects of Following Recommendations in the Dietary Guidelines for Americans
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Body Weight
- Obesity
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: None (Open Label)Primary Purpose: Basic Science
Participation Requirements
- Age
- Between 35 years and 64 years
- Gender
- Only males
Description
This will be a 32-week study including baseline testing (week 0), increased physical activity in all groups, pre-diet testing (week 5), an 8-week controlled feeding period, post-diet testing (week 14), a follow-up period of dietary education and observation, and end of study testing (week 32). Durin...
This will be a 32-week study including baseline testing (week 0), increased physical activity in all groups, pre-diet testing (week 5), an 8-week controlled feeding period, post-diet testing (week 14), a follow-up period of dietary education and observation, and end of study testing (week 32). During the 8 week feeding, participants will be randomly assigned one of the following diets: DGA Mediterranean diet pattern at sufficient energy level to maintain body weight (energy balance) DGA Mediterranean diet pattern at a moderately reduced energy level (negative energy balance) TAD diet pattern at a moderately reduced energy level (negative energy balance) In the follow-up phase, the investigators will evaluate how multiple factors may influence body weight management, including previous dietary exposure, as well as the role of cognitive function, executive function, genetics, habitual diet, physical activity, eating behavior, stress and stress responsivity, metabolic flexibility and gut microbiome.
Tracking Information
- NCT #
- NCT04293224
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Kevin D Laugero, PhD USDA, Western Human Nutrition Research Center