Receptor for Advanced Glycation End Products (RAGE) Polymorphisms In Inflammatory Bowel Disease
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Inflammatory Bowel Diseases
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Other
Participation Requirements
- Age
- Younger than 125 years
- Gender
- Both males and females
Description
This study aims: To investigate the association of both allelic and genotypic -374T/A and -429T/C polymorphisms and inflammatory bowel disease. To correlate the relation between the studied SNPs , disease activity and the clinical features of the disease. Subjects and Methods: This is a case control...
This study aims: To investigate the association of both allelic and genotypic -374T/A and -429T/C polymorphisms and inflammatory bowel disease. To correlate the relation between the studied SNPs , disease activity and the clinical features of the disease. Subjects and Methods: This is a case control study. The study will include 90 patients diagnosed as IBD. Patients will be recruited from outpatient department of Elraghey Liver Hospital in Assiut University Hospital.The clinical disease activity was calculated using the Montreal classification of disease activity and Crohn's Disease Activity Index (CDAI) for UC and CD patients, respectively (Silverberg et al., 2005). -Also, 90 apparently healthy subjects (age and sex matched with the patient group) will be included as control group.
Tracking Information
- NCT #
- NCT04286659
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Elham Abdelsamie Assiut University