Recruitment

Recruitment Status
Not yet recruiting
Estimated Enrollment
Same as current

Summary

Conditions
  • Bariatric Surgery
  • Obesity
Type
Interventional
Phase
Not Applicable
Design
Allocation: N/AIntervention Model: Single Group AssignmentIntervention Model Description: Physical training group or sedentary control group (Study 1) and Postbariatric group or non-bariatric control group (Study 2)Masking: None (Open Label)Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 45 years
Gender
Both males and females

Description

Randomized controlled trial (Study 1) will feature post-bariatric patients in outpatient care at the Policlinica Piquet Carneiro. After recruitment, patients will be randomized into 2 groups: training group (TG) and control group (CG). The patients allocated to TG will perform, for 6 months, a aerob...

Randomized controlled trial (Study 1) will feature post-bariatric patients in outpatient care at the Policlinica Piquet Carneiro. After recruitment, patients will be randomized into 2 groups: training group (TG) and control group (CG). The patients allocated to TG will perform, for 6 months, a aerobic and resistance exercises program. The sessions of physical training will be 3 times a week and will include 20 min of walking and 40 min of resistance exercises involving large muscle groups, with 8-12 repetitions in load corresponding to 70-85% of 1 repetition maximum (RM). The CG will not perform physical exercises during the experiment period. The outcomes will be assessed by dual energy X-ray emission densitometry (DXA); high resolution peripheral quantitative computed tomography (HR-pQCT), 1 RM and cardiopulmonary exercise test; biochemical analysis (blood lipid profile, blood glucose and biomarkers of bone formation and absorption and calcium metabolism); venous occlusion plethysmography and nailfold videocapillaroscopy; blood pressure measurement; accelerometry; International Physical Activity Questionnaire and 36-Item Short-form Health Survey. The cross-sectional study (Study 2) will have 2 groups: post-bariatric patients group (BG) and control group (CG) - non-bariatric controls. Outcomes will be assessed by DXA; HR-pQCT; handgrip strength and biochemical analysis (blood lipid profile, blood glucose and biomarkers of bone formation and absorption and calcium metabolism).

Tracking Information

NCT #
NCT04193397
Collaborators
Not Provided
Investigators
Principal Investigator: Luiz Guilherme K De Aguiar, PhD Rio de Janeiro State University, Rio de Janeiro, RJ, Brazil