Sickle Cell Uric Acid (SCUA) - Cohort Repository
Last updated on July 2021Recruitment
- Recruitment Status
- Enrolling by invitation
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Chronic Kidney Diseases
- Sickle Cell Disease
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 5 years and 29 years
- Gender
- Both males and females
Description
Sickle Cell Disease causes kidney injury over time, but it is not clear why some individuals have very significant chronic kidney disease and why some do not. The purpose of this research is to study whether having high levels of 'uric acid,' which is a naturally occurring molecule in the body that ...
Sickle Cell Disease causes kidney injury over time, but it is not clear why some individuals have very significant chronic kidney disease and why some do not. The purpose of this research is to study whether having high levels of 'uric acid,' which is a naturally occurring molecule in the body that may increase kidney injury and systemic inflammation, accelerates the progression of chronic kidney disease over time. Researchers will measure the number of participants that have high uric acid levels at the beginning of the study, as well as the number of participants that develop new high levels throughout the study. The study will also try to determine what causes the high uric acid levels in some patients but not others. The results of this study could help understand kidney injury and uric acid in sickle cell disease better.
Tracking Information
- NCT #
- NCT04190888
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Cristin Kaspar, MD Virginia Commonwealth University