Turner Syndrome Minipuberty Study
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- 60
Summary
- Conditions
- Gonadal Dysgenesis
- Infertility Female
- Ovarian Diseases
- Premature Menopause
- Premature Ovarian Failure
- Sex Chromosome Disorders
- Turner Syndrome
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Younger than 13 years
- Gender
- Only males
Description
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: The subjects will have twice an extra venapunction for collection of 3.5mL blood during their infancy, which is not stated in the guidelines for TS. There is very little risk for adverse events as...
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: The subjects will have twice an extra venapunction for collection of 3.5mL blood during their infancy, which is not stated in the guidelines for TS. There is very little risk for adverse events associated with this blood sample collection, however it is an extra procedure. The outcome parameters will not be helpful for individual study participants, however they are likely to help clinicians and researchers in understanding how the ovarian function operates develops in girls with TS. Furthermore, these markers could be used to estimate the ovarian reserve and the urgency of fertility preservation in young females with TS. This information could help clinicians, patients and their parents in decision making.
Tracking Information
- NCT #
- NCT04189406
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Janielle vd Velden, MD, PhD Paediatric endocrinologist, Radboudumc, Nijmegen
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