Meal Timing and Blood Pressure
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Blood Pressure
- Neurovascular Control
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentIntervention Model Description: The interventional study model used will consist of a time-restricted feeding intervention.Masking: None (Open Label)Primary Purpose: Basic Science
Participation Requirements
- Age
- Between 50 years and 65 years
- Gender
- Both males and females
Description
Healthy adults experience a 10-20% decrease in night-time blood pressure, compared with day-time blood pressure. However, 20-40% of middle-aged adults do not demonstrate a decrease in blood pressure. Abnormal blood pressure patterns are linked to sleep disturbances, hypertension, and associated with...
Healthy adults experience a 10-20% decrease in night-time blood pressure, compared with day-time blood pressure. However, 20-40% of middle-aged adults do not demonstrate a decrease in blood pressure. Abnormal blood pressure patterns are linked to sleep disturbances, hypertension, and associated with elevated cardiovascular risk and mortality. Additionally, abnormal diurnal blood pressure patterns are associated with impaired neurovascular control of the circulation, contributing to an increased risk of hypertension, stroke, and cardiovascular disease. Importantly, midlife is the critical period for implementing interventions to prevent or delay future cardiovascular disease. Recent data demonstrates that time-restricted feeding may normalize blood pressure patterns. The overall goal of this study is to determine if time-restricted feeding normalizes blood pressure patterns and improves neurovascular control. The research aims are: To determine the effect of meal timing on blood pressure patterns in middle-aged adults. To determine the effect of meal timing on neurovascular control in middle-aged adults.
Tracking Information
- NCT #
- NCT04133701
- Collaborators
- American Heart Association
- Investigators
- Principal Investigator: Jill N Barnes, PhD University of Wisconsin, Madison