Mycoplasma Infection Rate and Macrolides Resistance in Children With Acute Respiratory Tract Infection
Last updated on July 2021Recruitment
- Recruitment Status
- Not yet recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Respiratory Tract Infections
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Younger than 18 years
- Gender
- Both males and females
Description
This research center is a cross-sectional investigation and study, 8 centers including Shanghai children's medical center recruit the outpatient respiratory infection cases into the group, 6 centers including Shanghai children's medical recruit children with community-acquired pneumonia in hospital ...
This research center is a cross-sectional investigation and study, 8 centers including Shanghai children's medical center recruit the outpatient respiratory infection cases into the group, 6 centers including Shanghai children's medical recruit children with community-acquired pneumonia in hospital into the group All of the above cases in the group relevant clinical datas are collected, and complete clinical follow-up.Pharyngeal swabs or sputum specimens collected during the study were sent to Shanghai children's medical center for the detection of MP and macrolidene drug resistance genes. Azithromycin was administered orally or intravenously to outpatients who tested positive for mycoplasma pneumoniae by colloidal gold method.Finally, MP infection rate of children with respiratory diseases including outpatient (common cold, acute bronchitis and cough after infection) and hospitalization (community-acquired pneumonia) was statistically observed.The detection rate of MP macrolides drug resistance gene was isolated from respiratory disease cases.Sensitivity and specificity of MP rapid detection method (antigen and antibody detection rapid colloidal gold method) for diagnosis of MP infection;Effectiveness of azithromycin in treatment of MRMP infection.
Tracking Information
- NCT #
- NCT04126304
- Collaborators
- Beijing Children's Hospital
- Tianjin Children's Hospital
- Xi 'an children's hospital
- Shenzhen Children's Hospital
- Third Affiliated Hospital of Zhengzhou University
- Shanghai Children's Hospital
- Children's Hospital of Chongqing Medical University
- Wuhan Children's Hospital
- The First Affiliated Hospital of Guangzhou Medical University
- Investigators
- Principal Investigator: Yong Yin, master Shanghai Children's Medical Center