Assessing Health-related Quality of Life in Sarcoma Patients
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Sarcoma
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Cross-Sectional
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
The investigators will follow the EORTC QLG questionnaire development guidelines. First, a computerized search of the academic literature will be performed to identify all relevant HRQoL issues for and existing HRQoL questionnaires currently used among patients with sarcoma. In parallel, semi-struct...
The investigators will follow the EORTC QLG questionnaire development guidelines. First, a computerized search of the academic literature will be performed to identify all relevant HRQoL issues for and existing HRQoL questionnaires currently used among patients with sarcoma. In parallel, semi-structured interviews will be conducted worldwide with patients with sarcoma(N=154) and health care professionals (HCPs; N=30; phase 1a). The patient sample will be stratified to capture diversity across the sarcoma population tumour location (extremities, axial, head and neck, thorax, retroperitoneal/intra-abdominal and gynecological), stage (localized vs. metastatic disease ) and type or lines of treatment . This list of HRQoL issues generated by the a) literature search, b) relevant items from the Item Library, and c) semi-structured patient and HCP interviews, and will be consolidated into a comprehensive list of issues for all languages of collaborating countries. In phase 1b, the new list of HRQoL issues will be presented to another group of patients with sarcoma(N=475) and HCPs (N=30). Patients and HCPs will be asked to rate the HRQoL issues on relevance (4point Likert scale) and to prioritize the 25 most important issues.
Tracking Information
- NCT #
- NCT04071704
- Collaborators
- MOUNT SINAI HOSPITAL
- Radboud University
- Leiden University Medical Center
- Centre Leon Berard
- University Hospital Carl Gustav Carus
- Heidelberg University
- Johannes Gutenberg University Mainz
- University College London Hospitals
- Hospitales Universitarios Virgen del Rocío
- King Hussein Cancer Center
- Hippocration General Hospital
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
- Oslo University Hospital
- Royal National Orthopaedic Hospital NHS Trust
- Royal Marsden NHS Foundation Trust
- Bank of Cyprus Oncology Centre
- Beatson West of Scotland Cancer Centre
- National Cancer Institute, Naples
- Hospital San Carlos, Madrid
- University Hospital Southampton NHS Foundation Trust
- Institut Català d'Oncologia
- Maria Sklodowska-Curie Institute - Oncology Center
- University of Adelaide
- Investigators
- Principal Investigator: Olga Husson, PhD The Netherlands Cancer Institute Principal Investigator: Winette van der Graaf, PhD, MD The Netherlands Cancer Institute