The Effects of Renal Function and Atrial Fibrillation on Lipoproteins and Clot Structure/Function
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- 156
Summary
- Conditions
- Atrial Fibrillation
- Chronic Kidney Disease
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
This is a prospective, observational, blinded study that will be conducted in two parts. The first study will assess the relationship between lipids/lipoproteins and fibrin clot properties among anticoagulated atrial fibrillation patients with and without renal dysfunction. The second study will ass...
This is a prospective, observational, blinded study that will be conducted in two parts. The first study will assess the relationship between lipids/lipoproteins and fibrin clot properties among anticoagulated atrial fibrillation patients with and without renal dysfunction. The second study will assess the effects of statin therapy on lipids/lipoproteins and fibrin clot properties in anticoagulated atrial fibrillation patients with renal dysfunction. Renal dysfunction is defined as an estimated glomerular filtration rate below 50 ml/min/1.73m2 for the purposes for this trial.
Tracking Information
- NCT #
- NCT04043026
- Collaborators
- Liverpool Centre for Cardiovascular Science
- Liverpool Heart and Chest Hospital NHS Foundation Trust
- Liverpool John Moores University
- University of Leeds
- Investigators
- Principal Investigator: Wern Yew Ding University of Liverpool
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