Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
Same as current

Summary

Conditions
Pain
Type
Interventional
Phase
Phase 2
Design
Allocation: N/AIntervention Model: Single Group AssignmentIntervention Model Description: Within-subject studyMasking: None (Open Label)Masking Description: Study drug administration will be concealed from all study staff and participants to prevent bias in outcomes.Primary Purpose: Basic Science

Participation Requirements

Age
Between 18 years and 75 years
Gender
Both males and females

Description

This study will systematically evaluate whether a combination of pharmacotherapies can effectively alleviate chronic pain. Subjects will complete a screening session before completing 5 study sessions that will occur once weekly. Subjects will double-blind doses of study medications the morning of e...

This study will systematically evaluate whether a combination of pharmacotherapies can effectively alleviate chronic pain. Subjects will complete a screening session before completing 5 study sessions that will occur once weekly. Subjects will double-blind doses of study medications the morning of each experimental session, and will undergo standardized pain testing, as well as provide self-report ratings of drug effects, and cognitive tests.

Tracking Information

NCT #
NCT04036968
Collaborators
National Institute on Drug Abuse (NIDA)
Investigators
Principal Investigator: Kelly E Dunn, PhD Johns Hopkins University Principal Investigator: Claudia Campbell, PhD Johns Hopkins University