Reducing Iodine Dose Based on Lean Body Weight
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Body Weight
- Carcinoma, Hepatocellular
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: Double (Participant, Outcomes Assessor)Primary Purpose: Diagnostic
Participation Requirements
- Age
- Between 20 years and 125 years
- Gender
- Both males and females
Description
Currently, the contrast media dose is calculated based on total body weight. However, the human body is composed of adipose tissue and non-adipose tissue, and adipose tissue contributes little to the volume of distribution for contrast media. Therefore, iodine dose calculated based on lean body weig...
Currently, the contrast media dose is calculated based on total body weight. However, the human body is composed of adipose tissue and non-adipose tissue, and adipose tissue contributes little to the volume of distribution for contrast media. Therefore, iodine dose calculated based on lean body weight would be more personalized than merely considering total body weight. In addition, lowering the contrast media dose would be achievable by using virtual monoenergetic imaging at low keV. Therefore, we aimed to assess whether the acceptable image quality is achievable using low contrast media dose calculated based on lean body weight and low keV imaging for the detection of hepatocellular carcinoma.
Tracking Information
- NCT #
- NCT04027556
- Collaborators
- Siemens Corporation, Corporate Technology
- Investigators
- Principal Investigator: Jeong Min Lee, MD Seoul National University Hospital
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