Early Identification and Effective Management of Pediatric Sepsis
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Sepsis
- Septic Shock
- Severe Sepsis
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Younger than 18 years
- Gender
- Both males and females
Description
We intend to enroll pediatric sepsis patients at four PICUs and divide them into two groups based on clinical outcomes: severe sepsis group (patients who progress into severe sepsis), sepsis group (patients who do not progress in to severe sepsis). We intend to perform predictive modeling using mult...
We intend to enroll pediatric sepsis patients at four PICUs and divide them into two groups based on clinical outcomes: severe sepsis group (patients who progress into severe sepsis), sepsis group (patients who do not progress in to severe sepsis). We intend to perform predictive modeling using multivariable analyses of the novel biomarkers and derive a biomarker panel and algorithm for early diagnosis of severe sepsis. The predictive value of the biomarker panel for early identification of severe sepsis will be compared with established indices, such as PRISM III and pSOFA score.
Tracking Information
- NCT #
- NCT03996720
- Collaborators
- Shanghai Children's Medical Center
- Shanghai Children's Hospital
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
- Investigators
- Principal Investigator: Guoping Lu, MD Children's Hospital of Fudan University
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