A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Lymphoblastic Lymphoma, Childhood
- Lymphoma Non-Hodgkin
- NOTCH1 Gene Mutation
- Pediatric Cancer
- PTEN Loss
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 1 years and 18 years
- Gender
- Both males and females
Description
Research purpose: To investigate the efficacy and safety of SCCCG-LBL-2017 in Chinese children with LBL. To explore the feasibility of risk stratification of T-LBL by combining genotyping. To investigate the correlation between MDD and MRD in lymphoblastic lymphoma and prognosis. To investigate the ...
Research purpose: To investigate the efficacy and safety of SCCCG-LBL-2017 in Chinese children with LBL. To explore the feasibility of risk stratification of T-LBL by combining genotyping. To investigate the correlation between MDD and MRD in lymphoblastic lymphoma and prognosis. To investigate the role of PET/CT in the assessment of residual lymphoblastic lymphoma. To explore the effect of reducing HD-MTX dosage and shortening maintenance therapy time on the efficacy and survival of low-risk LBL patients. To explore the effect of prolonging the duration of maintenance therapy on the efficacy and survival of high-risk LBL patients.
Tracking Information
- NCT #
- NCT03971318
- Collaborators
- Not Provided
- Investigators
- Study Director: Zhen zijun Sun Yat-sen University
Get Well Soon