Use of Melatonin for Preventing POCD in Transurethral Prostate Resection Under Spinal Anesthesia
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Cognitive Dysfunction
- Melatonin
- Postoperative Complications
- Prostate Hyperplasia
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: randomized, parallel assignmentMasking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)Masking Description: triple maskingPrimary Purpose: Prevention
Participation Requirements
- Age
- Between 60 years and 125 years
- Gender
- Only males
Description
TURP is the most common surgical procedure performed on male patients over 60 years of age to treat benign prostatic hyperplasia. One of the concerns, since it compromises the quality of life, is postoperative cognitive dysfunction. It can be due to TURP Syndrome or to other causes, like changing th...
TURP is the most common surgical procedure performed on male patients over 60 years of age to treat benign prostatic hyperplasia. One of the concerns, since it compromises the quality of life, is postoperative cognitive dysfunction. It can be due to TURP Syndrome or to other causes, like changing the routine and circadian rhythm for patients with more susceptibility. The investigators postulate that melatonin premedication and use during the perioperative period could avoid cognitive impairment in patients undergoing TURP surgery that didn't develop major complications, like TURP Syndrome. Since anesthestic technic could also influence the outcome of POCD, only patients undergoing spinal anesthesia were included in the study,
Tracking Information
- NCT #
- NCT03966950
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Maria JC Carmona, PHD Associate Professor
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