PRGN-3006 Adoptive Cellular Therapy Relapsed or Refractory AML or High Risk MDS
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Acute Myeloid Leukemia
- Myelodysplastic Syndromes
- Type
- Interventional
- Phase
- Phase 1
- Design
- Allocation: N/AIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Both males and females
Description
This is a single center, nonrandomized, investigator-initiated Phase 1/1b safety and tolerability study. The safety and tolerability of PRGN-3006 T cells will be assessed following intravenous administration of escalating doses in patients with relapsed or refractory acute myeloid leukemia (AML) or ...
This is a single center, nonrandomized, investigator-initiated Phase 1/1b safety and tolerability study. The safety and tolerability of PRGN-3006 T cells will be assessed following intravenous administration of escalating doses in patients with relapsed or refractory acute myeloid leukemia (AML) or higher risk myelodysplastic syndromes (MDS). This study will enroll in two phases: an initial dose escalation phase followed by a dose expansion phase.
Tracking Information
- NCT #
- NCT03927261
- Collaborators
- Precigen, Inc
- Investigators
- Principal Investigator: David A Sallman, MD H. Lee Moffitt Cancer Center and Research Institute Principal Investigator: Nelli Bejanyan, MD Moffitt Cancer Center
Get Well Soon