The Effects of Attenuated Versus Inactivated Flu Vaccine in Twin Sets
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Influenza
- Type
- Interventional
- Phase
- Phase 4
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentMasking: None (Open Label)Primary Purpose: Basic Science
Participation Requirements
- Age
- Between 2 years and 20 years
- Gender
- Both males and females
Description
This is a Phase IV study of licensed influenza vaccines. The study requires 10 monozygotic and 10 dizygotic sets of twins (40 total participants) to enroll. The duration of the study for an individual volunteer will be 4 weeks including screening and active participation. The study has a total of 3 ...
This is a Phase IV study of licensed influenza vaccines. The study requires 10 monozygotic and 10 dizygotic sets of twins (40 total participants) to enroll. The duration of the study for an individual volunteer will be 4 weeks including screening and active participation. The study has a total of 3 visits. First visit: Procedures during this visit are: Informed consent process, enrollment, study assessments, 20 ml blood draw, and vaccination. Participants will be randomized to receive either LAIV or IIV. The time required to complete the first study visit will be about 30-40 minutes. 2nd (day 7 post vaccination) and 3rd (day 28 post vaccination ) visit: 20 ml blood will be obtained and the visit will take approximately 15 minutes.
Tracking Information
- NCT #
- NCT03898986
- Collaborators
- National Institutes of Health (NIH)
- National Institute of Allergy and Infectious Diseases (NIAID)
- Investigators
- Principal Investigator: Philip M Grant Assistant Professor of Medicine (Infectious Diseases)
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