Influence of Maternal Exercise on Infant Skeletal Muscle and Metabolomics
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Exercise
- Type
- Interventional
- Phase
- Not Applicable
- Design
- Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: comparing 3 exercise interventions to a control (non-exercise) groupMasking: Double (Care Provider, Investigator)Masking Description: the clinicians and investigators taking measures are blinded to group assignmentPrimary Purpose: Prevention
Participation Requirements
- Age
- Between 18 years and 35 years
- Gender
- Only males
Description
Is offspring skeletal muscle function and metabolism imprinted by regular maternal exercise? What offspring metabolome markers are altered with regular maternal exercise? The investigators will use a randomized design of 160 women to either exercise intervention (aerobic training, resistance trainin...
Is offspring skeletal muscle function and metabolism imprinted by regular maternal exercise? What offspring metabolome markers are altered with regular maternal exercise? The investigators will use a randomized design of 160 women to either exercise intervention (aerobic training, resistance training, or both) or usual care (controls). Infant cord tissue and blood will be sampled at birth while blood will be sampled at 1 month of age. Similarly, infant neuromotor and morphometric examinations will be performed at 1 month. and at 1-month of age via blood sample, neuromotor, and morphometric examinations. The rationale for the project is to elucidate the effects of maternal exercise on offspring health outcomes and determine specific metabolic targets predictive of offspring long-term disease risk.
Tracking Information
- NCT #
- NCT03838146
- Collaborators
- American Heart Association
- Investigators
- Not Provided
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