The CHYMASE Angiotensin-(1-12) Axis in Cardiovascular Disease
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Cardiovascular Disease
- Type
- Observational
- Design
- Observational Model: CohortTime Perspective: Prospective
Participation Requirements
- Age
- Between 40 years and 125 years
- Gender
- Both males and females
Description
Study is to determine the presence of the human sequence on Ang-(1-12) in the plasma of normal male and female normotensive, hypertensive and/or resistant hypertensive subjects. To measure concentrations of Ang-(1-12) in either serum or spot urine collections from male and female normal, hypertensiv...
Study is to determine the presence of the human sequence on Ang-(1-12) in the plasma of normal male and female normotensive, hypertensive and/or resistant hypertensive subjects. To measure concentrations of Ang-(1-12) in either serum or spot urine collections from male and female normal, hypertensive and/or resistant hypertensive subjects. To assess whether chymase activity can be detected in human serum and urine using the radiolabeled amino acid sequence of 1251-Ang-(1-12)
Tracking Information
- NCT #
- NCT03826745
- Collaborators
- Wake Forest University
- Investigators
- Principal Investigator: Henry A Punzi, MD Punzi Medical Center
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