Role of Eosinophil in Fibrogenesis of Systemic Sclerosis
Last updated on July 2021Recruitment
- Recruitment Status
- Active, not recruiting
- Estimated Enrollment
- 60
Summary
- Conditions
- Systemic Scleroderma
- Systemic Sclerosis
- Type
- Observational
- Design
- Observational Model: Case-ControlTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 66 years
- Gender
- Both males and females
Description
it will assess the activation state of blood eosinophils in SSc patients compared to healthy controls (ECP production in vitro, surface activation markers, whole transcriptome array, ..). it will also study skin eosinophils and their recruitment (extracellular eosinophil granules, eotaxins productio...
it will assess the activation state of blood eosinophils in SSc patients compared to healthy controls (ECP production in vitro, surface activation markers, whole transcriptome array, ..). it will also study skin eosinophils and their recruitment (extracellular eosinophil granules, eotaxins production in skin, ..)
Tracking Information
- NCT #
- NCT03816189
- Collaborators
- GlaxoSmithKline
- Investigators
- Principal Investigator: Guillaume Lefevre, MD University Hospital, Lille
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