Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
80

Summary

Conditions
  • Lymphoma
  • Solid Tumor
Type
Interventional
Phase
Phase 1
Design
Allocation: Non-RandomizedIntervention Model: Single Group AssignmentMasking: None (Open Label)Primary Purpose: Treatment

Participation Requirements

Age
Between 18 years and 125 years
Gender
Both males and females

Description

This is a first-in-human, open-label, multicenter, dose escalation study designed to determine the safety and tolerability of RPTR-147 as a monotherapy and in combination with Pembrolizumab in patients with selected solid tumors or lymphomas. The study will include 2 dosing periods: A Dose Escalatio...

This is a first-in-human, open-label, multicenter, dose escalation study designed to determine the safety and tolerability of RPTR-147 as a monotherapy and in combination with Pembrolizumab in patients with selected solid tumors or lymphomas. The study will include 2 dosing periods: A Dose Escalation (Phase 1) followed by an Expansion (Phase 2).

Tracking Information

NCT #
NCT03815682
Collaborators
Merck Sharp & Dohme Corp.
Investigators
Study Director: Daniel Vlock, MD Repertoire Immune Medicines