Recruitment

Recruitment Status
Recruiting
Estimated Enrollment
32

Summary

Conditions
Alcohol Use Disorder
Type
Interventional
Phase
Not Applicable
Design
Allocation: RandomizedIntervention Model: Parallel AssignmentIntervention Model Description: active vs. sham stimulationMasking: Triple (Participant, Care Provider, Investigator)Masking Description: double-blindPrimary Purpose: Treatment

Participation Requirements

Age
Between 22 years and 55 years
Gender
Both males and females

Description

This study aims to examine the effect of rTMS on alcohol drinking behavior in an observed laboratory setting. Participants with AUD will be recruited and admitted to the inpatient unit for the whole study. After a brief detoxification period, they will receive 3 weeks of rTMS while in the research u...

This study aims to examine the effect of rTMS on alcohol drinking behavior in an observed laboratory setting. Participants with AUD will be recruited and admitted to the inpatient unit for the whole study. After a brief detoxification period, they will receive 3 weeks of rTMS while in the research unit. Before and after the 3 weeks of stimulation, participants will participate in a decision-making experiment where they can choose to have an alcoholic drink or the equivalent amount of money that the drink would cost (alcohol self-administration sessions). The investigators will examine their response to alcohol, as well as their performance on tasks that relate to impulsivity and memory. Participants will also undergo an MRI scan (with spectroscopy) before and after the stimulation period to look at changes in the medial prefrontal cortex of the brain. Participants will then meet with a study physician for 6 weeks after the study for assessments of alcohol use and medical management sessions.

Tracking Information

NCT #
NCT03809286
Collaborators
Not Provided
Investigators
Principal Investigator: Jonathan Wai New York State Psychiatric Institute
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