A Prospective Evaluation of the Peri-operative Hypoxia in Breast Cancer
Last updated on July 2021Recruitment
- Recruitment Status
- Recruiting
- Estimated Enrollment
- Same as current
Summary
- Conditions
- Breast Cancer - Female
- Type
- Observational
- Design
- Observational Model: OtherTime Perspective: Prospective
Participation Requirements
- Age
- Between 18 years and 125 years
- Gender
- Only males
Description
Three tumor samples will be obtained after the patient is under anaesthesia, Prior to starting surgery (Sample A) The middle intra-operative sample, which will be collected when half the tumour has been devascularized (i.e., somewhere midway during the surgery). (Sample B) A third post excision (ano...
Three tumor samples will be obtained after the patient is under anaesthesia, Prior to starting surgery (Sample A) The middle intra-operative sample, which will be collected when half the tumour has been devascularized (i.e., somewhere midway during the surgery). (Sample B) A third post excision (anoxic sample C). These tumour tissue samples will be stored as snap frozen, in RNA later and as paraffin sections. To understand the effects induced by acute hypoxia that sets in during surgery in breast cancer. To study this, clinical samples (Tumor biopsies) will be obtained during and stored for future genomic and proteonomic evaluations.
Tracking Information
- NCT #
- NCT03797482
- Collaborators
- Not Provided
- Investigators
- Principal Investigator: Rajendra Badwe Director, tata Memorial Centre
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