Predictive Value of Renal Venous Flow Profiles for Acute Kidney Injury After Cardiac Surgery

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Each year, more than three million patients undergo cardiac surgery worldwide. Acute kidney injury (AKI) complicates as many as 36% of these procedures, doubling total hospital costs. Even minor changes of serum creatinine in the postoperative period have been associated with decreased survival. Whe...

Each year, more than three million patients undergo cardiac surgery worldwide. Acute kidney injury (AKI) complicates as many as 36% of these procedures, doubling total hospital costs. Even minor changes of serum creatinine in the postoperative period have been associated with decreased survival. When dialysis is required, short-term mortality may exceed 60%. Moreover, AKI predicts increased long-term mortality regardless of other risk factors even when kidney function has recovered. Despite this, clinicians have limited tools to preoperatively identify patients at risk for AKI. Identification of high-risk patients preoperatively could impact clinical decision making around surgical technique (e.g. off-pump) and timing of surgery in addition to perioperative management (hemodynamic monitoring, use of certain drugs, fluid management etc.). The prospective single-center study investigates whether abnormal preoperative Doppler-based renal venous flow profiles as surrogates for right heart failure predict risk of acute kidney injury after cardiac surgery.

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